Invivogen LPS-EB (Standard) (LPS from E. coli O111:B4) tlrl-eblps

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品　　牌：Invivogen

产品型号：Invivogen LPS-EB (Standard) (LPS from E. coli O111:B4) tlrl-eblps

制造厂商：Invivogen

适用范围：全阶段

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　　Lipopolysaccharide from E. coli O111:B4

　　InvivoGen provides LPS-EB with two grades of purity:

• LPS-EB is a standard lipopolysaccharide (LPS) preparation. It was extracted by a phenol-water mixture.

　　LPS-EB contains other bacterial components, such as lipopeptides, and therefore stimulates both TLR4 and TLR2.

• Ultra-pure LPS-EB was extracted by successive enzymatic hydrolysis steps and purified by the phenol-TEA-DOC extraction protocol. 

　　Ultrapure LPS-EB only activates the TLR4 pathway.

　　Specifications

　　LPS-EB

　　Specificity: TLR4 and TLR2 agonist.

　　Solubility: 5 mg/ml in water.

　　Working concentration: 10 ng - 10 μg/ml.

　　LPS-EB Ultrapure

　　Specificity: TLR4 agonist.

　　Solubility: 5  x 10e6 EU/ml in water.

　　Working concentration: 10e1 - 10e4 EU/ml.

　　Contents

　　LPS-EB

• 5 mg lipopolysaccharide from E. coli 0111:B4 (LPS-EB ).

• 1.5 ml endotoxin-free water.

　　LPS-EB Ultrapure

• 5 x 10⁶EU  ultrapure lipopolysaccharide from E. coli 0111:B4 (LPS-EB Ultrapure).

• 1.5 ml endotoxin-free water.

　　Products are shipped at room temperature.

　　Upon receipt product should be stored at -20°C.

　　Lyophilized product is stable 1 year at -20°C.

　　Resuspended product is stable 1 month at 4°C and 6 months at -20°C.

　　Citations

　　2018 Nat Commun. 9(1):996.

　　The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages.

　　Chu LH. et al.

　　2018 Sci Rep. 8(1):3788.

　　ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.

　　Lee BL. et al.

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